Agilent 6490 Triple Quad LC/MS

Description Agilent 6490 Triple Quad LC/MS Overview The Agilent 6490 Triple Quad LC/MS System is a high-performance liquid chromatography–tandem mass spectrometry platform engineered for laboratories requiring maximum sensitivity, wide dynamic range, and reliable quantitation across complex sample types. At the core of this system is an advanced ion handling design that enhances ion capture and transmission efficiency, enabling detection of compounds at extremely low concentration levels. This increased sensitivity allows analysts to confidently measure trace compounds that may be difficult to detect with conventional LC-MS/MS systems. The 6490 is specifically optimized for quantitative workflows using multiple reaction monitoring (MRM). Its high-speed acquisition capabilities enable accurate monitoring of a large number of transitions within a single run, making it highly effective for multi-residue and high-throughput analyses. The system maintains excellent reproducibility and signal stability, even when processing demanding sample matrices such as biological fluids, environmental extracts, or food products. To support modern chromatography, the instrument is fully compatible with fast UHPLC methods. It is capable of capturing narrow peak widths while maintaining sufficient data density for precise quantitation. Rapid polarity switching further increases efficiency, allowing simultaneous analysis of compounds requiring both positive and negative ionization without extended run times. The system also features an optimized collision cell design that improves fragmentation efficiency while reducing background interference, resulting in cleaner spectra and more reliable identification of target analytes. Combined with robust ionization options such as electrospray ionization (ESI), the platform can be adapted to a wide range of analytical applications. Agilent 6490A Triple Quad LC/MS is offered fully refurbished and tested, in working condition. Includes: Agilent 6490A Triple Quad LC/MS Jet Stream Source Two (2) Vacuum Pump Data System 90-Day Warranty Optional: Agilent UHPLC Front End Systems (1260 or 1290 Infinity Series) Premium Refurbishment with Extended Warranty Disclaimer: All brand names and trademarks are the property of their respective owners and are used for identification only. We are not an authorized dealer. Software, if included, is not transferable or upgradable.